HOW ANDEMBRY WORKS
GROUNDBREAKING
HAE TREATMENT
ANDEMBRY is the first and only approved prophylaxis treatment for HAE patients proven to work differently from other options by inhibiting Factor XIIa at the top of the HAE pathway.

How ANDEMBRY Works
- Inhibits the HAE cascade at the top to prevent HAE attacks
- Factor XII is the first protein activated in the contact activation pathway
- Factor XIIa plays a key role in an HAE attack by converting prekallikrein to kallikrein when C1-esterase inhibitor (C1INH) is missing or dysfunctional
HMWK = high-molecular weight kininogen
YOUR JOURNEY, WITHOUT INTERRUPTIONS
ANDEMBRY is a powerful prophylaxis treatment with a noticeable reduction in HAE attacks beginning at Week 1.
Photo does not depict actual patient

Photo does not depict actual patient
YOUR JOURNEY, WITHOUT INTERRUPTIONS
ANDEMBRY is a powerful prophylaxis treatment with a noticeable reduction in HAE attacks beginning at Week 1.

