INDICATION: ANDEMBRY is a prescription medicine used to prevent attacks of Hereditary Angioedema (HAE) in children 12 years of age and older.
ANDEMBRY Provides Significant Reduction in HAE Attacks
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A median reduction of >99% was calculated because at least half of the ANDEMBRY-treated patients experienced a complete reduction in monthly HAE attack rates compared to placebo. Patients receiving ANDEMBRY in the clinical trial experienced an adjusted average of 89% (LS; least squares) reduction in monthly HAE attack rate compared to placebo.
* With all HAE medications, attacks can still occur. Patients should always have a rescue medication.
† At 6 months.
LS, least squares
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Attack reduction has been maintained throughout ongoing clinical trials§
§ 2+ years and counting.
Subcutaneous self-injection delivered in ≤15 seconds via a convenient autoinjector
No reports of injection-site pain¶
¶ In the VANGUARD pivotal phase 3 trial. Patients in the pivotal study and open-label extension study experienced injection-site redness, itching, and bruising.
Innovation in Action
Only ANDEMBRY, a monoclonal antibody, inhibits FXIIa at the top of the HAE pathway
Innovation in Action
Only ANDEMBRY, a monoclonal antibody, inhibits FXIIa at the top of the HAE pathway